Patients were treated. Patients were treated. All 10 patients were treated by radical prostatectomy or-gan – confined disease with one exception. 4 of treated patients after treatment had a median follow error in follow-up of 48 months.. Results: Median age at diagnosis was 67 years. Median follow-up was 76 months. Overall, 34 patients had progression. Overall, median time to progression was 18 months. The first re – biopsy was positive for cancer in 48 patients and negative in 44 patients. The 5-year actuarial progression-free probability was 82 percent for patients with negative first , compared to 50 percent of patients with positive first re – biopsy and re – biopsy, it was 97 percent for patients with persistent negative biopsy compared to 42 percent in patients with persistent positive biopsy (p2 positive cores at diagnosis were significant predictor of progression.

Conclusions: Negative in patients with prostate cancer on AS low volume disease re – biopsy has the result of the first repeated biopsy strong impact. In the prediction of progression of the disease. Patients with positive first re – biopsy should be taken into consideration for treatment. Pathological progression usually occurs in the first 2 years of follow up. Intensive biopsy protocol in the first 2-3 years is required to recognize and provide treatment to patients at high risk of progression.Winston Laboratories studied activated looking for a partner by sales and marketing strength commercialize recent civamide polish 0.

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